- How long can a person live with the JC virus?
- How common is JC virus?
- How is the JC virus transmitted?
- Can stress cause MS?
- Can the JC virus be cured?
- What are the symptoms of the JC virus?
- What are the first signs of PML?
- What does a positive JC virus mean?
- What is a high JCV titer?
- What does PML feel like?
- How fast does PML progress?
- Is MS caused by a virus?
- Can you recover from PML?
- Is PML reversible?
How long can a person live with the JC virus?
It is caused by reactivation of the John Cunningham virus (JCV) and infection of glial cells.
It is often fatal, with a median life expectancy of less than six months following onset of symptoms .
Reports of PML afflicting immunocompetent patients are extremely rare but not unknown..
How common is JC virus?
The John Cunningham virus, known more commonly as the JC virus, is a very common virus in the United States. According to the World Journal of Neurosciences, between 70 and 90 percent of people in the world have the virus.
How is the JC virus transmitted?
The high prevalence of JCV in urine and in sewage and the stability of the viral particles observed suggests that contaminated water, food, and fomites could be the vehicles of JCV transmission through the oral route.
Can stress cause MS?
Can stress cause MS? There is no definitive evidence to say that stress is a cause for MS. Stress can, however, make it difficult for a person to manage MS symptoms. Many patients also report that stress triggered their MS symptoms or caused a relapse.
Can the JC virus be cured?
There is no cure once the JC virus enters the brain and causes PML, but if the infection is caught soon enough there are treatments that may reduce the risk of longterm complications.
What are the symptoms of the JC virus?
They can be different depending on the area of your brain that’s affected, but the most common signs are:Clumsiness.Weakness that gets worse.Changes in personality.Trouble speaking.Vision problems.
What are the first signs of PML?
These symptoms include:general weakness that steadily gets worse.clumsiness and balance issues.sensory loss.difficulty using your arms and legs.changes to vision.loss of language skills.facial drooping.personality changes.More items…•
What does a positive JC virus mean?
If the blood test finds JC virus (JCV positive), this indicates that you are at a higher risk of developing PML, although for most people the risk is still small.
What is a high JCV titer?
This JCV index reflects the degree of humoral immunity to circulating virus proteins. Higher titers suggest the immune system has been re-exposed to viral particles or to the virus itself, and implicate new enhanced replication of virus or inadequacy of cell-mediated immunity, the main force controlling virus spread.
What does PML feel like?
The symptoms of PML are diverse, since they are related to the location and amount of damage in the brain, and may evolve over the course of several weeks to months. The most prominent symptoms are clumsiness; progressive weakness; and visual, speech, and sometimes personality changes.
How fast does PML progress?
Symptoms can progress quickly over weeks and include mental deterioration, vision loss, speech disturbances, lack of coordination, paralysis, and coma. Specific symptoms relate to the affected areas of the brain by PML. Seizures can occur in 1 out of 5 people. How is PML diagnosed?
Is MS caused by a virus?
Multiple sclerosis (MS) is a demyelinating disorder of unknown etiology, possibly caused by a virus or is virus-triggered. Several viruses, including herpesviruses, were suggested as etiologic agents or risk factors for exacerbation in the course of illness but none have been shown to be irrefutably linked.
Can you recover from PML?
There is no cure for PML but one-year survival has increased from 10% to 50% in HIV-infected individuals treated with highly active antiretroviral therapy (HAART).
Is PML reversible?
When PML results from reversible immunosuppression, as in patients with multiple sclerosis (MS) who are receiving monoclonal antibodies, the immediate cessation of the offending agent is recommended.